söndag 18 augusti 2024

Effective Diagnosis and Treatment of Empty Nose Syndrome

The article "Diagnosis and Management of Empty Nose Syndrome" provides a comprehensive overview of Empty Nose Syndrome (ENS), a condition that arises primarily as a result of surgical interventions on the nasal turbinates, leading to a loss of tissue and subsequent symptoms that can significantly affect patients' quality of life.

Key Discoveries:

Definition and Symptoms: ENS is characterized by paradoxical nasal obstruction, dryness, and a sense of suffocation despite having a patent nasal airway. The condition was first described by Eugene Kern and Monika Stenkvist in 1994, highlighting its association with tissue loss following turbinate resection. The article emphasizes that ENS is distinct from atrophic rhinitis, although they share some overlapping symptoms.

Iatrogenic Nature: The research underscores that ENS is primarily an iatrogenic disorder, often resulting from aggressive surgical techniques such as turbinectomy or laser ablation. These procedures can lead to significant alterations in nasal airflow sensation and mucosal integrity, which are critical for effective nasal breathing.

Nasal Airflow Sensation: The authors discuss the physiological relationship between nasal airflow sensation and the respiratory center, suggesting that changes in airflow sensation can lead to the perception of nasal obstruction. This insight is crucial for understanding the underlying mechanisms of ENS and guiding treatment approaches.

Management Strategies: The article reviews various management strategies for ENS, noting that many patients have previously failed conservative medical management and have been misdiagnosed. While aggressive nasal hygiene and moisturizers may provide limited relief, surgical options such as submucosal implantation of acellular dermis have shown promise. In a study cited, patients reported subjective improvements in symptoms post-implantation, including enhanced sense of smell and reduced dryness.

Assessment Tools: The authors highlight the importance of comprehensive assessment tools, such as the SNOT-25 questionnaire, which includes ENS-specific questions to aid in the recognition and diagnosis of the condition. This tool helps clinicians better understand the patient's experience and tailor management strategies accordingly.

Conclusions:
The research concludes that ENS is a complex and often underrecognized condition that requires a nuanced understanding of nasal physiology and airflow dynamics. The authors advocate for a cautious approach to turbinate surgery, emphasizing the need for preserving mucosal integrity to prevent ENS. They also call for further research into the pathophysiology of ENS and the development of effective treatment modalities. The findings underscore the importance of clinical suspicion and thorough assessment in diagnosing ENS, as well as the need for individualized treatment plans that address the unique symptoms and experiences of each patient.

In summary, the article provides valuable insights into the diagnosis and management of ENS, highlighting the need for awareness among clinicians and the importance of preserving nasal function during surgical interventions.

SLEEP IMPAIRMENT IN PATIENTS WITH EMPTY NOSE SYNDROME

C-C Huang 1, C-C Lee 2, P-W Wu 3, C-C Chuang 4, Y-S Lee 5, P-H Chang 6, C-C Huang 1, C-H Fu 1, T-J Lee 7
Abstract

Background: Empty nose syndrome (ENS) is characterized by paradoxical nasal obstruction that usually occurs after turbinate surgery. Patients with ENS may also experience significant psychiatric symptoms and sleep dysfunction, which negatively affect the quality of life of affected subjects. This study aimed to evaluate sleep impairment and sleepiness in patients with ENS.

Methods: Patients with ENS and control participants were recruited prospectively. The Sino-Nasal Outcome Test-25 (SNOT-25), Empty Nose Syndrome 6-item Questionnaire (ENS6Q), Epworth Sleepiness Scale (EpSS), and modified sleep quality index (MSQI) were used to evaluate the participants before and after nasal surgery.

Results: Forty-eight patients with ENS and forty-eight age- and sex-matched control subjects were enrolled. The SNOT-25, ENS6Q, EpSS, and MSQI scores in the ENS group were all significantly higher than those in the control group before and after surgery. After surgery, ENS patients all exhibited significant improvements in SNOT-25, ENS6Q, EpSS, and MSQI scores. Regression analysis revealed that SNOT-25 score was a significant predictor of EpSS and MSQI in preoperative evaluations. ENS patients experiencing daytime sleepiness suffered from significantly more "dryness of nose" and "suffocation" than those not experiencing daytime sleepiness.

Conclusions: Patients with ENS experienced significantly impaired sleep quality and sleepiness. Nasal reconstruction surgery improved the sleep quality of ENS patients. The severity of sleep dysfunction is associated with the severity of ENS symptoms. Recognizing individuals with significant sleep impairment and sleepiness and providing appropriate management are critical issues for ENS patients.